Informasi Detil Paper

Judul: Piperonil Alcohol as Precusor for Synthesis Derivative C-9154 Antibiotic from Safrole
Penulis: Healthy Kainama  || email:
Jurnal: Prosiding FMIPA Universitas Pattimura 2010 Vol. 1 no. 1 - hal. 133-140 Tahun 2010  [ MIPA ]
Keywords:  Piperonil alcohol, derivative C-9154 antibiotic, safrole
Abstract: It has been done the synthesis of Piperonil alcohol as precursor in derivative of C-9154 antibiotic from safrole. Safrole was isolated from cullilawan oil. The synthesis was started by isomerisation of safrole with KOH in ethanol at reflux for 8 hours, then oxidation of isosafrole with KMnO4 using Tween 80 as the catalist in acid at 30oC for 15 minutes to give piperonal. The further experimental stages were reduction of piperonal with NaBH4 afforded piperonil alcohol in 90,7% yield.
File PDF: Download fulltext PDF PDF

<<< Previous Record Next Record >>>