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Judul: | Penggunaan Krim Ekstrak Batang Dan Daun Suruhan (Peperomia Pellucida L.H.B.K) Dalam Proses Penyembuhan Luka Bakar Pada Tikus Putih (Rattus Norvegicus) |
Penulis: | Nur Fitri & Syaran Wael || email: info@mx.unpatti.ac.id |
Jurnal: | Molucca Medica Vol. 8 no. 1 - hal. 82-97 Tahun 2015 [ Kedokteran ] |
Keywords: | s: Stems and leaves suruhan extract cream (Peperomia pellucida L.H.B.K), Bum grade IIb, Healing process of burns, Fibroblast. |
Abstract: | Peperomia pellucida L.H.B.K also known as suruhan in Indonesia is herb plant belong to family piperaceae. This study aims to determine the insertion effect of stems and leaves suruhan extract cream towards bum healing process on white mice (Rattus norvegicus) and to compare differentiation effect between control group and the treatment group of stems and leaves suruhan extract cream. The study was an experimental research with completely randomized design. Test animals were divided into three grcups, each .group consisting .of three white mice. The fast .grou.p was the negatif control group (Aquades), the second group was the positive control group (Bioplacenton®), and the third group was the treatment group of stems and leaves suruhan extract cream. The wound's diameter and histopathology of fibroblast were observed and used as indicator of burn healing process. The Burns grade IIb were treated and observed the healing effects for 20 days. Data were statistically analyzed using Anova method continued with Least The result showed that stems and leaves suruhan extract cream have effect towards bum healing process in white mice. The result also showed that the treatment group of stems and leaves suruhan extract cream and positive control group influences the burn healing process significantly when compare with control negative group. Meanwhile, the treatment group of stems and leaves suruhan extract cream didn't have different effect of burn healing process significantly with control positive group. |
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