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Judul: Effect of Ethanol Extract Gambir Laut Leaves (Clerodendrum Inerme L) to Ovaries Weight of Mice
Penulis: Chomsa Dintasari Umi Baszary & Feliks Pattinama  || email:
Jurnal: Prosiding FMIPA 2016 Vol. 1 no. 1 - hal. 219-221 Tahun 2016  [ Prosiding ]
Keywords:  Clerodendrum inerme L., ovary, anti-estrogen.
Abstract: This study aims to determine the effect of ethanol extract Gambir Laut leaves against ovarian performance mice. The treatment consists of the control mice (P0) were given distilled water and ethanol extract treatment Gambir Laut leaves : P1 (350 mg / ml), P2 (700 mg / ml) and P3 (1400 mg / ml) at a dose of 0.2 ml / 20- 30 g / BW. The results showed that ethanol extract Gambir Laut l eaves caused a decrease in ovarian weight with ovarian weight is 0.04 g P0, is 0.02 g P1, is 0.02 g P2, and 0.01 g P3. Ovarian weight loss occurs because the active compounds in the ethanol extract Gambir Laut leaves as saponins and flavonoids are anti-estrogen that may interfere with the development of ovarian follicles.
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