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Judul:	Aktivitas Antimalaria Ekstrak Metanol Kulit Batang Cempedak Terhadap Plasmodium Falciparum Sensitif dan Resisten-Klorokuin
Penulis:	Maximus M. Taek \|\| email: maxi_taek@yahoo.com
Jurnal:	Molucca Medica Vol. 4 no. 1 - hal. 37-41 Tahun 2011 [ Kedokteran ]
Keywords:	A. champeden, antimalarial activity, in-vitro, P. falciparum, chloroquine-sensitive and resistant.
Abstract:	Methanol extract of Cempedak (Artocarpus champeden) stem bark was screened for its antimalarial activity against chloroquine-sensitive and chloroquine-resistant Plasmodium falciparum according to an in-vitro testing procedure. The test was done in-vitro with non-synchronized cultures of 3D7 (chloroquine-sensitive) and G-2300 (chloroquine-resistant) strains of P. falciparum for 48 hours. The IC50 values found for the methanol extract were 4.230 μg/mL toward 3D7 strain, and 16.580 μg/mL toward G-2300 strain. At the same test condition, chloroquine has the IC50 of 0.003 μg/mL toward 3D7 strain.
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